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Prolonged indoleamine 2,3-dioxygenase-2 (IDO2) activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection(PASC, or long COVID)

Prolonged indoleamine 2,3-dioxygenase-2 (IDO2) activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection(PASC, or long COVID) https://ift.tt/EIlQukV Prolonged indoleamine 2,3-dioxygenase-2 (IDO2) activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection(PASC, or long COVID) PASC encompass fatigue, post-exertional malaise and cognitive problems. The abundant expression of the tryptophan-catabolizing enzyme IDO2 in fatal/severe COVID-19, led us to determine whether IDO2 is expressed and active in PASC, and may correlate with pathophysiology.

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